As if losing 1-0 at home to Belarus in their opening qualifier was not enough, France travel to Bosnia and Herzegovina on Tuesday without forwards Guillaume Hoarau, Loïc Rémy and Louis Sah.
FC Carmiel Safed of Israel took first place in preliminary round Group B with a 1-0 win against hosts West Hungary though coach Oded Cotter admitted: "We had a little bit of luck."
Hungary 0-1 Wales Brian Flynn's side will be sure of a play-off place if they avoid defeat in Italy on Tuesday after Robson Kanu's goal gave them victory in Hungary.
Poland 1-1 Ukraine Yevgen Selezniov's late goal earned Yuriy Kalitvintsev's side a draw after Ireneusz Jelen had given their UEFA EURO 2012 co-hosts the lead.
Lech Wałęsa, former president of Poland, was at the Polish launch of the Friends of UEFA EURO 2012 scheme, along with Józef Młynarczyk, Maryla Rodowicz and Robert Korzeniowski.
San Marino will look to change the course of history when they meet Sweden in Group E of qualifying having lost 6-0 and 5-0 in their two previous encounters.
Moldova 1-0 Faroe Islands Home captain Artur Ioniţă scored the only goal ten minutes from time before Finnur Justinussen was dismissed for the visitors.
Azerbaijan 3-2 Albania Bernhard Lippert's side nearly nearly squandered a three-goal lead but clung on to record their first Group 10 win in seven attempts.
Tottenham Hotspur FC look set to be without Michael Dawson for their first three group games after the defender was ruled out for six to eight weeks with knee ligament damage.
Philipp Lahm captained Germany to their opening 1-0 Group A victory in Belgium and told UEFA.com: "We were the better team over the 90 minutes and could have won by more."
The excellent working ties between UEFA and the Latvian Football Federation were underlined during UEFA president Michel Platini's visit to the Baltic state.
Elias Charalambous was pleased after Cyprus drew 4-4 in Portugal but told UEFA.com: "I think that if we had concentrated a bit more in the game we might have got a win. "
Pontus Wernbloom scored his first two Sweden goals to defeat Hungary 2-0 and said the doubts about whether he would even win his ninth cap proved a spur to his performance.
Group A rivals Turkey and Belgium meet for the first time in a EURO qualifier having encountered one another several times in the past en route to the FIFA World Cup.
Belarus goalkeeper Yuri Zhevnov told UEFA.com: "It's going to take a bit of time before we realise what we've done," after captaining his nation to a stunning 1-0 win in France.
Spain began the defence of their title with an efficient 4-0 win in Liechtenstein and Xabi Alonso said: "We tried to apply the same style and the same intensity as during the World Cup."
England may have begun Group G with a 4-0 defeat of Bulgaria but they go to Switzerland on Tuesday with Michael Dawson added to their injury list while the home side also miss key men.
Jermain Defoe postponed a groin operation to line up for England against Bulgaria and after his Wembley hat-trick in a 4-0 win the striker said: "I'm glad I didn't have it now."
Switzerland and Ukraine confirmed their places in the play-offs as group winners but Sweden and the Czech Republic missed chances to do likewise as the group stage goes down to the wire.
Spain started the defence of their European crown with a comfortable win in Liechtenstein but France lost at home to Belarus as qualifying for Poland/Ukraine began in earnest.